A Case of Hyperandrogenism, Insulin Resistance, and Acanthosis Nigricans Syndrome; Increase in Proliferating Cell Nuclear Antigen and Decrease in Loricrin in Acanthosis Nigricans
نویسندگان
چکیده
Vol. 28, No. 5, 2016 637 Received May 27, 2014, Revised December 17, 2014, Accepted for publication August 18, 2015 Corresponding author: Yutaka Hatano, Department of Dermatology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Yufu City, Oita 879-5593, Japan. Tel: 81-97-586-5882, Fax: 81-97-586-5889, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology pISSN 1013-9087ᆞeISSN 2005-3894 Ann Dermatol Vol. 28, No. 5, 2016 http://dx.doi.org/10.5021/ad.2016.28.5.637
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Comparison of Insulin resistance in obese women with and without Acanthosis Nigricans
Background and aim: Acanthosis nigricans (AN) is characterized by hyperpigmented velvety plaques of body folds and neck. Insulin can have a role in the pathogenesis of this disease and hyperinsulinemia as a consequence of insulin resistance may stimulate the formation of the characteristic plaques of AN. In this study insulin resistance was compared in obese women with and without AN.</sp...
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